ea0025p173 | Endocrine tumours and neoplasia | SFEBES2011
Kalhan Atul
, Garibi Borzo
, Jasani Bharat
, Kidd Mark
, Modlin Irvin
, Pfragner Roswitha
, Rees Aled
, Ham Jack
Introduction: Neuroendocrine tumors of GI tract are a heterogeneous group of rare neoplasms that secrete peptides and amines. These tumors are highly vascular and their vascularity reflects increased tumour related angiogenesis. Adenosine, a major regulator of angiogenesis, is released by enhanced degradation of ATP, during cellular stress, damage and hypoxia.Material and methods: The expression of adenosine receptors (AR) was investigated in two human n...